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TGF-Beta 1

The normal range for TGF-Beta 1 levels are below 2380 pg/ml. Elevated levels are extremely common with CIRS/mold clients. TGF-Beta 1 is a regulatory protein that has an important function in the innate immune system. High levels indicate an overactive immune system.  Elevated TGF-Beta 1 can cause symptoms of brain fog, shortness of breath and dry cough. If it’s extremely elevated, it may be related to other conditions such as neurological, autoimmune, or other chronic illnesses.

Lowering TGF-Beta 1 requires reducing exposure to inflammatory triggers and toxic mold. Avoiding grains and amylose can be important in people with high TGF-Beta 1 because grains are contaminated with mold and cause chronic gut inflammation.


The normal range for MSH is 35-81 pg/ml. Low levels of MSH are very common among people with CIRS/mold illness. It is an important hormone of the nervous system and has receptors in the hypothalamus. It can help protect the body from candida infections.

The functions of MSH include reducing inflammation, controlling cytokine release, and regulating other hormones such as ADH and VIP. If MSH is low, the client may be susceptible to leaky gut, insomnia, candida overgrowth, pain, diarrhea, nasal MARCoNS, reduced sex hormones, increased thirst, and increased urination.

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